Searchable abstracts of presentations at key conferences in endocrinology

ea0054oc1 | (1) | NuclearReceptors2018

Heterodimerization of retinoid X receptor with xenobiotic nuclear receptors occurs in the cytoplasmic compartment of cell in a ligand independent manner

Dash Amit K , Yende Ashutosh S , Tyagi Rakesh K

The ‘Nuclear Receptor (NR) Super-family’ is a group of ligand modulated transcription factors with 48 members presently identified in human genome. NRs regulate most of the physiological processes of the body ranging from metabolism to reproduction. Retinoid X Receptor (RXR) is one of the important members of this NR superfamily. It serves as a heterodimeric partner of several other members of this superfamily including two major xenobiotic nuclear receptors i.e. Pre...